Younger patients with comorbidities are at higher risk of mortality: COVID-19 Study of First phase

• This study is conducted to observe the association of diabetes (DM), hypertension (HTN) and chronic kidney disease (CKD) on the prognosis and mortality of COVID-19 infection in hospital admitted patients with above mentioned comorbidities.
• Study on association of underlying comorboties and progression of Covid-19 infection amonghs 2586 Hospitalized Patients at Sir Ganga Hospital
• Females with comorbidities were at higher risk of mortality than males

India

healthysoch

New Delhi, June 26, 2022:

A retrospective study was conducted by researchers of Sir Ganga Ram Hospital on 2586 COVID-19 Hospitalized patients who were admitted in the hospital from April 8,2020 to October 4,2020 (First Phase) to observe the association of Diabetes (DM), Hypertension (HT) and chronic kidney disease  (CKD) on the prognosis and mortality of COVID-19 infection in Hospitalized patients.

The study has been published on 25^th June 2022 in Molecular and Cellular Biochemistry, Springer Nature. According to Dr Rashmi Rana , Author & Consultant , Department of Research , Sir Ganga Ram Hospital , “ Our study also found that females were relatively at higher risk of mortality as compared to males having same Comorbid conditions except hypertensive patients.”

According to Dr Vivek Ranjan , Co-author & Chairperson , Department of Blood Transfusion, Sir Ganga Ram Hospital , “ Study showed risk of the severity of COVID-19 infection in younger patients with  underlying comorbidities were found to be relatively at higher risk of severity of disease as well as to mortality compared to elderly patients with similar underlying condition.”

According to Dr Atul Gogia, Co-author and Senior Consultant , Department of Medicine ,” In our study patients with Chronic Kidney Disease were found to be more prone to disease progression , complications and mortality followed by Hypertension and Diabetes.”

Out of 2586 patients , 779(30.1%) needed ICU admission where as 1807(69.9%) were not admitted in ICU. Out of 2586 Hospitalized patients of COVID-19 infection , 2269 (87.7%) and the mortality was in 317(12.3%) patients.

According to Dr D.S.Rana, Co-author and Chairperson, Department of Renal Sciences ,” On comparing the impact of multiple co-morbidities  with the severity of COVID-19 infection , it was found that presence of Comorbity poses greater risk of ICU admission . As the number of comorbidities increased , the risk of severity of COVID-19 infection also increases significantly.”

In the present study we also found that presence of comorbidity poses greater risk of ICU admission . Patients with diabetes and hypertension were related to longer recovery period. As the number of comorbidities increased , the risk of severity of COVID-19 infection also increases significantly.

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