Beware Drug Interactions With Supplements

Morning Medtalks with Dr KK Aggarwal

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New Delhi, April 18, 2019 :

1. The High Court has asked the Jammu and Kashmir government to respond to a Public Interest Litigation seeking directions to allow sale and usage of e-cigarettes in the state. A division bench of Chief Justice Gita Mittal and Justice Tashi Rabstan granted six weeks to the government to file the response after state’s additional advocate General Shah Aamir sought the time.

2. Vitamin D has been reported to have a wide range of benefits. However, a recent case study indicates that excessive use of vitamin D can cause kidney damage in people who are not deficient in the vitamin. The article was published online April 8 in the Canadian Medical Association Journal.

3. Revealing the added sugars in packaged foods and beverages would prevent nearly one million cases of type 2 diabetes and cardiovascular disease in the United States and save about $62 billion in societal costs, new research suggests. The study is published online April 15 in Circulation and is the first to assess the health impacts and costs of the FDA’s added-sugar labeling policy

4. A new scientific statement from the American Heart Association (AHA) lays out the rationale and specifics for multimodal cardiac rehabilitation (CR) for patients with cancer, with a clear eye toward gaining equal footing for these services among third-party payers.

Canagliflozin the wonder drug

A new landmark clinical trial shows that canagliflozin lowers the risk of kidney failure by a third in people with Type 2 diabetes and kidney disease. The trial involved 4,401 participants in 34 countries. Canagliflozin also was found to reduce the risk of major cardiovascular events.

Canagliflozin increases the excretion of glucose through the kidneys. It has already been approved by the Food and Drug Administration to lower blood glucose in patients with Type 2 diabetes and to reduce the risk of major adverse cardiovascular events in patients with Type 2 diabetes and existing heart disease.

A paper describing the findings of the CREDENCE trial was published today in The New England Journal of Medicine and presented at the International Society of Nephrology’s World Congress of Nephrology in Melbourne.

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Beware Drug Interactions With Supplements

Over 67% of patients with cancer and 77% of patients with osteoporosis take supplements.

Over 34% of people who take a prescription medication also take at least one dietary supplement, a rate that increases to 61% in adults older than 60 years.

In some cases, supplements have pharmacologic effects similar to those of drugs prescribed to patients. Adding a supplement may then result in increased side effects of the drug in the form of pharmacodynamic interactions.

Several supplements marketed for diabetes or blood sugar control have hypoglycemic effects.

Glucosamine and turmeric are frequently used for osteoarthritis but can interact with drugs such as anticoagulants, which are used for other indications.

The Author of this article is Dr K K Aggarwal

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